Short Communication - Archives of Industrial Biotechnology (2024) Volume 8, Issue 4
Quantitative proteomics: Methods and clinical implications
Amiya Kumar Behera*
Department of Pharmacy, Biju Patnaik University of Technology, Odisha, India
- *Corresponding Author:
- Amiya Kumar Behera
Department of Pharmacy
Biju Patnaik University of Technology
Odisha, India
E-mail:beheraamiya@gmail.com
Received: 23-Jul-2024, Manuscript No. AAAIB-24-144203; Editor assigned: 25-Jul-2024, PreQC No. AAAIB-24-144203 (PQ); Reviewed: 06-Aug-2024, QC No. AAAIB-24-144203; Revised: 17-Aug-2024, Manuscript No. AAAIB-24-144203 (R); Published: 22-Aug-2024, DOI: 10.35841/aaaib- 8.4.219
Citation: Behera AK. Quantitative proteomics: Methods and clinical implications. Arch Ind Biot. 2024; 8(4):219
Proteomics, the large-scale study of proteins, their structures, and functions, has become an indispensable tool in modern biological and medical research. Among the various branches of proteomics, quantitative proteomics focuses on determining the abundance of proteins in different biological samples, allowing researchers to gain insights into cellular mechanisms and disease states [1], [2]
Protein microarrays are another powerful technique for quantitative proteomics. They involve the immobilization of thousands of proteins or antibodies on a solid surface, allowing simultaneous detection and quantification of protein interactions [3].
Quantitative proteomics enables the identification of patient-specific protein expression profiles, leading to personalized treatment plans. Assessment of protein changes in response to drug treatment, aiding in the development of more effective therapies [4], [5]
Quantitative proteomics provides insights into the molecular mechanisms underlying diseases, revealing potential therapeutic targets and pathways. The development of quantitative proteomics-based diagnostic assays is on the rise, offering more precise and early detection of diseases [6], [7]
Future advancements are expected to address these challenges, with innovations in MS technology, improved bioinformatics tools, and the development of more robust and cost-effective methods. Integrating quantitative proteomics with other omics technologies, such as genomics and metabolomics, will further enhance our understanding of biological systems and disease processes [8], [9]
Quantitative proteomics is a powerful approach for studying protein abundance and dynamics in biological systems. Its applications in biomarker discovery, personalized medicine, and clinical diagnostics hold great promise for improving healthcare outcomes. As technologies continue to advance, quantitative proteomics will undoubtedly play a pivotal role in shaping the future of biomedical research and clinical practice [10].
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