Research Article - Microbiology: Current Research (2021) Volume 5, Issue 3

Pseudomonas aeruginosa strains obtained from hospital infections with various resistances in Tehran, Iran.

Abstract

Objectives: Improper and inappropriate use of antibiotics is one of the possible factors affecting the transmission of antibiotic resistance is because Pseudomonas aeruginosa is one of the most serious pathogenic bacteria in hospital environments and resistant It is an antibiotic that causes problems in treatment. This study aims to determine multiple resistances Pseudomonas aeruginosa has been treated with antibiotics, arsenic and metals. Meterials and methods: In this study, 23 strains of Pseudomonas aeruginosa were isolated from clinical specimens. For review resistance of these bacteria to penicillin antibiotics was used by Kirby-Bauer method. The minimum concentration C.I.M. and minimum lethal concentrations C.B.M. of antibiotics and heavy metals (cadmium, mercury) and arsenate Tubal dilution, agar and growth were performed in agar plate, respectively. Results: In this study, the highest and lowest MIC values obtained in Pseudomonas aeruginosa for metals, respectively. 8 and 3 cadmiums (0.6 and 4.9 μg/ml), mercury (<0.12 and 4 μg/ml) and arsenate (10 × 256 μg/ml) of 23 strains, 84% to the antibiotic carbonicillin, 63% to piperacillin and 100% to 103 Arsenic and cadmium were resistant. Also, 82.6% of the strains were resistant to mercury. Conclusion: The results of this study showed that Pseudomonas aeruginosa strains have multiple resistance to arsenic, metals and the antibiotics are car penicillin and piperacillin.