Perspective - Journal of Pregnancy and Neonatal Medicine (2023) Volume 7, Issue 5
Neonatal infections: The role of maternal health and immunization.
Federico Carbone *
Department of Immunology, University of Manitoba, Canada
- *Corresponding Author:
- Federico Carbone
Department of Immunology, University of Manitoba, Canada
E-mail: Federico@canada.com
Received: 27-Sept-2023, Manuscript No. AAPNM-23-115939; Editor assigned: 28-Sept-2023, PreQC No. AAPNM-23-115939; Reviewed: 12-Oct-2023, QC No. AAPNM-23-115939; Revised: 17-Oct-2023, Manuscript No. AAPNM-23-115939(R); Published: 24-Oct-2023, DOI:10.35841/aapnm -7.5.167
Citation: Carbone F. Neonatal infections: The role of maternal health and immunization. J Preg Neonatal Med. 2023;7(5):167
Introduction
The birth of a child is a momentous occasion in any family's life, filled with hope and anticipation. However, it also marks the beginning of a vulnerable phase for the newborn, as they enter a world full of potential dangers, including infectious diseases. Neonatal infections pose a significant threat to the health and well-being of infants, and addressing this challenge requires a multifaceted approach. One crucial aspect of this approach is the role of maternal health and immunization [1].
Maternal health plays a pivotal role in determining the risk of neonatal infections. A mother's health during pregnancy can directly impact the health of her newborn. Several factors contribute to this relationship, starting with the mother's own immunity. When a pregnant woman is in good health and has an adequate immune response, she can pass on protective antibodies to her baby through the placenta. These antibodies, specifically immunoglobulin G (IgG), provide the newborn with temporary immunity against certain infections, offering a crucial layer of protection during the first few months of life [2].
Immunization is another critical component in the fight against neonatal infections. Vaccines have been one of the most effective public health interventions in history, preventing countless cases of infectious diseases and saving millions of lives. Immunizing pregnant women against specific infections can help protect both the mother and her newborn. One of the most well-known examples of maternal immunization is the tetanus vaccine. Tetanus, a potentially deadly bacterial infection, can be transmitted to newborns through unclean delivery practices. Immunizing pregnant women with tetanus toxoid can prevent maternal and neonatal tetanus, reducing the risk of this devastating disease [3].
Another key vaccine for pregnant women is the influenza vaccine. Pregnant women are more susceptible to severe complications from the flu, and getting vaccinated during pregnancy not only protects the mother but also confers some immunity to the newborn during the critical early months of life when they cannot receive the vaccine themselves. This practice helps reduce the risk of severe influenza-related illness in both mother and baby. Pertussis can be especially dangerous for newborns, who are at higher risk of severe complications and death [4].
Immunization not only protects individual newborns but also contributes to herd immunity. When a significant portion of the population is immunized, the spread of infectious diseases is reduced, protecting those who cannot receive vaccines, such as newborns too young to be immunized and individuals with certain medical conditions [5].
Conclusion
Neonatal infections are a serious concern that can have devastating consequences for infants and their families. Maternal health and immunization play a pivotal role in reducing the risk of neonatal infections. By ensuring that pregnant women receive appropriate care, including immunizations against preventable diseases, and by promoting infection control practices in healthcare settings, we can protect vulnerable newborns and give them the best possible start in life. The collaboration between healthcare providers, public health authorities, and expectant mothers is key to achieving this goal and ensuring that every newborn has a healthy and infection-free beginning.
References
- Denizli M, Capitano ML, Kua KL. Maternal obesity and the impact of associated early-life inflammation on long-term health of offspring. Front Cell Infect Microbiol. 2022;12:940937.
- Sanidad KZ, Amir M, Ananthanarayanan A, et al. Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity. Sci Immunol. 2022;7(72):eabh3816.
- Cinicola B, Conti MG, Terrin G, et al. The protective role of maternal immunization in early life. Front Pediatr. 2021;9:638871.
- Dawod B, Marshall JS, Azad MB. Breastfeeding and the developmental origins of mucosal immunity: how human milk shapes the innate and adaptive mucosal immune systems. Curr Opin Gastroenterol. 2021;37(6):547-56.
- Moore SE. Early life nutritional programming of health and disease in The Gambia. Journal of developmental origins of health and disease. 2016;7(2):123-31.
Indexed at, Google Scholar, Cross Ref
Indexed at, Google Scholar, Cross Ref
Indexed at, Google Scholar, Cross Ref
Indexed at, Google Scholar, Cross Ref