Commentary - Insights in Nutrition and Metabolism (2024) Volume 8, Issue 1
Micronutrients: Tiny players, big effects on cellular biology.
Bezawit Abate *
Department of Biomedicine, Switzerland, University of Basel, Switzerland.
- *Corresponding Author:
- Bezawit Abate
Department of Biomedicine, Switzerland, University of Basel, Switzerland.
E-mail: abate.b@unibas.ch
Received: 01-Jan-2024, Manuscript No. AAINM-24-131731; Editor assigned: 02-Jan-2024, PreQC No AAINM-24-131731 (PQ) Reviewed:16-Jan-2024, QC No. AAINM-24-131731 Revised:22-Jan-2024, Manuscript No. AAINM-24-131731 (R); Published:26-Jan-2024, DOI:10.35841/aainm-8.1.186
Citation: Abate B. Micronutrients: Tiny players, big effects on cellular biology. Insights Nutr Metab. 2024;8(1):186
Introduction
Micronutrients, encompassing essential vitamins and minerals, may be small in size but wield profound effects on cellular biology. These nutrients, required in small quantities, play indispensable roles in various cellular processes, influencing everything from energy metabolism to DNA synthesis. While often overshadowed by macronutrients, the significance of micronutrients cannot be overstated. In this article, we delve into the world of micronutrients, exploring their critical roles and impact on cellular biology [1].
Vitamins are organic compounds that serve as coenzymes or precursors for essential metabolic reactions within cells. From vitamin A, essential for vision and immune function, to vitamin K, crucial for blood clotting, each vitamin plays a unique role in maintaining cellular health and function [2].
Minerals, though needed in smaller amounts compared to macronutrients, are equally vital for cellular processes. Calcium, for instance, is integral to muscle contraction and nerve signaling, while iron is essential for oxygen transport in red blood cells. Without these minerals, cellular function would be compromised [3].
Micronutrients such as vitamins C and E, along with minerals like selenium and zinc, act as antioxidants, protecting cells from oxidative damage caused by free radicals. By neutralizing these harmful molecules, micronutrients help prevent cellular aging and reduce the risk of chronic diseases such as cancer and cardiovascular disease [4].
Several micronutrients, including folate, vitamin B12, and zinc, are involved in DNA repair and synthesis processes. These nutrients play crucial roles in maintaining genomic stability, ensuring accurate replication, and preventing mutations that could lead to diseases like cancer [5].
Micronutrients participate in energy metabolism by serving as cofactors for enzymes involved in cellular respiration and ATP production. B vitamins, for example, play key roles in converting carbohydrates, fats, and proteins into usable energy, ensuring cells have the fuel needed to function optimally [6].
Vitamins A, C, D, and E, along with minerals like zinc and selenium, are essential for supporting immune function. These micronutrients help regulate immune cell proliferation, differentiation, and activity, enhancing the body's ability to defend against pathogens and infections [7].
Certain micronutrients, such as vitamin D and magnesium, play roles in hormone regulation. Vitamin D, often referred to as the "sunshine vitamin," is involved in the synthesis of hormones like calcitriol, which regulates calcium and phosphorus levels in the body, crucial for bone health and other physiological functions [8].
Micronutrients like vitamin B6, folate, and iron are involved in neurotransmitter synthesis, which is essential for proper brain function and mental health. Deficiencies in these micronutrients have been linked to conditions such as depression, anxiety, and cognitive impairment [9].
Calcium, magnesium, phosphorus, and vitamin D are key micronutrients involved in maintaining bone health and integrity. These nutrients contribute to bone mineralization, density, and strength, reducing the risk of osteoporosis and fractures. Micronutrients such as vitamins A, C, and E, along with minerals like zinc and selenium, play crucial roles in skin health and wound healing. These nutrients support collagen synthesis, protect against UV damage, and promote tissue repair, maintaining the integrity and vitality of the skin [10].
Conclusion
Micronutrients may be small in size, but their impact on cellular biology is vast and multifaceted. From supporting energy metabolism to maintaining DNA integrity and regulating immune function, these essential vitamins and minerals are indispensable for overall health and well-being. By ensuring adequate intake of micronutrients through a balanced diet or supplementation when necessary, individuals can optimize cellular function and reduce the risk of chronic diseases, promoting longevity and vitality.
References
- Sharma A, Patni B, Shankhdhar D, et al. Zinc–an indispensable micronutrient. Physiol Mol Biol Plants. 2013;19:11-20.
- Elmadfa I, Meyer AL. The role of the status of selected micronutrients in shaping the immune function. Endocr Metab Immune Disord Drug Targets. 2019;19(8):1100-15.
- Clemens S. Zn–a versatile player in plant cell biology. Cell biology of metals and nutrients. 2010:281-98.
- Opazo MC, Coronado-Arrázola I, Vallejos OP, et al. The impact of the micronutrient iodine in health and diseases. Crit Rev Food Sci Nutr. 2022;62(6):1466-79.
- Irimie AI, Braicu C, Pasca S, et al. Role of key micronutrients from nutrigenetic and nutrigenomic perspectives in cancer prevention. Medicina. 2019;55(6):283.
- Patel P, Yadav K, R Ganapathi T. Small and hungry: microRNAs in micronutrient homeostasis of plants. MicroRNA. 2017;6(1):22-41.
- Arigony AL, de Oliveira IM, Machado M, et al. The influence of micronutrients in cell culture: a reflection on viability and genomic stability. Biomed Res Int. 2013;2013.
- Malvi UR. Interaction of micronutrients with major nutrients with special reference to potassium. Karnataka J Agric Sci. 2011;24(1).
- Kaspari M. The invisible hand of the periodic table: how micronutrients shape ecology. Annu Rev Ecol Evol Syst. 2021;52:199-219.
- Arshad R, Gulshad L, Haq IU, et al. Nanotechnology: A novel tool to enhance the bioavailability of micronutrients. Food Sci Nutr. 2021;9(6):3354-61.
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