Journal of Clinical and Experimental Toxicology

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +44-1518-081136

Case Report - Journal of Clinical and Experimental Toxicology (2023) Volume 7, Issue 3

Emerging trends in clinical & experimental toxicology: Challenges and opportunities.

Lina Yang*

Department of Environmental Toxicology, International University of Korea, Jinju, South Korea

*Corresponding Author:
Lina Yang
Department of Environmental Toxicology
International University of Korea
Jinju, South Korea
E-mail: linay@adm.korea.ac.kr

Received: 05-June-2023, Manuscript No. AACETY-23-101362; Editor assigned: 06-June-2023, PreQC No. AACETY-23-101362 (PQ); Reviewed: 19-June-2023, QC No.AACETY-23-101362; Revised: 21-June-2023, Manuscript No. AACETY-23-101362 (R); Published: 28-June-2023, DOI: 10.35841/aacety-7.3.143

Citation: Yang L. Toxicity testing methods: From the clinical trials to experimental models. J Clin Exp Tox. 2023 ;7(3):143

Visit for more related articles at Journal of Clinical and Experimental Toxicology

Introduction

Clinical and experimental toxicology play pivotal roles in understanding and mitigating the adverse effects of toxic substances. However, the field faces new challenges with the emergence of novel substances, changing environmental factors, and technological advancements. This review focuses on emerging trends in clinical and experimental toxicology, exploring the challenges and opportunities they bring [1].

Nanotoxicology

The rise in nanotechnology has led to the development and utilization of various nanomaterials in a wide range of applications. However, the potential adverse effects of nanomaterials on human health and the environment raise concerns. Nanotoxicology aims to understand the unique properties and mechanisms of nanomaterial toxicity. This emerging trend poses challenges in terms of standardized testing methods, characterization techniques, and risk assessment frameworks. Addressing these challenges will enable the safe and sustainable use of nanomaterials while harnessing their opportunities for technological advancements [2].

Environmental Toxicology

Environmental toxicology focuses on the impact of pollutants and contaminants on ecosystems and human health. With increasing industrialization, urbanization, and climate change, understanding the complex interactions between environmental factors and toxic substances is crucial. Emerging trends in environmental toxicology include the study of emerging contaminants, such as microplastics and pharmaceuticals, as well as the integration of ecological and human health risk assessments. These trends require interdisciplinary collaboration, advanced monitoring techniques, and regulatory frameworks that account for the complexities of environmental exposures [3].

Big Data Analytics

The increasing availability of large datasets presents opportunities and challenges in clinical and experimental toxicology. Big data analytics can uncover patterns, associations, and predictive models that enhance our understanding of toxicology. Integration of diverse data sources, such as clinical data, genomics, exposomics, and environmental data, enables comprehensive assessments of toxicity. However, challenges lie in data quality, standardization, and privacy issues. Developing robust analytical approaches and data sharing mechanisms is essential for harnessing the potential of big data analytics in toxicology research and risk assessment [4].

Regulatory Implications

The emergence of new trends in toxicology also poses regulatory challenges. Regulatory frameworks need to adapt to accommodate novel substances, emerging contaminants, and personalized medicine approaches. Harmonization of international regulations, integration of alternative testing methods, and proactive risk assessment approaches are crucial for effective regulation in the rapidly evolving field of toxicology [5].

Conclusion

Emerging trends in clinical and experimental toxicology present both challenges and opportunities for the field. Nanotoxicology, environmental toxicology, personalized medicine, and big data analytics are just a few examples of these trends. Addressing challenges related to standardization, interdisciplinary collaboration, ethics, and regulations is essential to harness the opportunities these trends offer. By embracing these emerging trends, clinical and experimental toxicology can continue to evolve and contribute to the protection of human and environmental health in an ever-changing world.

References

  1. Malinowska B, Baranowska-Kuczko M. Opportunities, challenges and pitfalls of using cannabidiol as an adjuvant drug in COVID-19. Int J Mol Sci. 2021; 22(4):1986.

    2. Indexed at, Google Scholar, Cross Ref

  2. Singh B, Abdelgawad ME, Ali Z et al. Towards more predictive, physiological and animal-free in vitro models: advances in cell and tissue culture 2020 conference proceedings.

    3. Indexed at, Google Scholar, Cross Ref

  3. Gaiaschi L, Roda E, Favaron C. The power of a novel combined anticancer therapy: challenge and opportunity of micotherapy in the treatment of Glioblastoma Multiforme. Biomed Pharmacother. 2022; 155:113729.

    4. Indexed at, Google Scholar, Cross Ref

  4. Li S, Xia M. Review of high-content screening applications in toxicology. Arch Toxicol. 2019; 93:3387-96.

    5. Indexed at, Google Scholar, Cross Ref

  5. Tveden-Nyborg P, Bergmann TK, Lykkesfeldt J. Basic & clinical pharmacology & toxicology policy for experimental and clinical studies. Basic Clin Pharmacol Toxicol. 2018; 123(3):233-5.

    6. Indexed at, Google Scholar, Cross Ref

Get the App