Journal of Infectious Diseases and Medical Microbiology

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Perspective - Journal of Infectious Diseases and Medical Microbiology (2024) Volume 8, Issue 2

Clinical manifestations of common infectious diseases

Devon Govarik *

Department of Dermatology, University of Pennsylvania, USA

*Corresponding Author:
Devon Govarik
Department of Dermatology, University of Pennsylvania, USA
E-mail: dgovarik4@ edu

Received: 22-Feb-2024, Manuscript No. AAJIDMM-24-142962; Editor assigned: 26-Feb-2024, PreQC No. AAJIDMM -24-142962 (PQ); Reviewed: 11-Mar-2024, QC No. AAJIDMM -24-142962; Revised: 14- Mar-2024, Manuscript No. AAJIDMM -24-142962 (R); Published: 19- Mar-2024, DOI:10.35841/aaagim-8.2.191

Citation: : Govarik Devon. Clinical manifestations of common infectious diseases. J Infect Dis Med Microbiol. 2024;8(2):191.

Introduction

Infectious diseases, caused by pathogenic microorganisms such as bacteria, viruses, parasites, or fungi, manifest in a variety of clinical symptoms depending on the pathogen involved, the mode of transmission, and the host’s immune response. Understanding these clinical manifestations is crucial for diagnosis, treatment, and prevention. This article explores the clinical manifestations of several common infectious diseases. Influenza, a viral infection caused by influenza viruses, typically presents with sudden onset of fever, chills, muscle aches, headache, fatigue, and respiratory symptoms such as cough, sore throat, and runny or stuffy nose. The severity of symptoms can vary widely, from mild to severe, sometimes leading to complications such as pneumonia, especially in high-risk groups like the elderly, young children, and individuals with underlying health conditions [1, 2].

Tuberculosis (TB), caused by Mycobacterium tuberculosis, primarily affects the lungs but can spread to other organs. Pulmonary TB manifests as a chronic cough lasting more than three weeks, chest pain, hemoptysis (coughing up blood), and systemic symptoms like fever, night sweats, and weight loss. Extrapulmonary TB can affect the lymph nodes, bones and joints, central nervous system, kidneys, and other organs, leading to symptoms specific to the affected area, such as swollen lymph nodes, back pain, or neurological deficits. Malaria, a mosquito-borne parasitic infection caused by Plasmodium species, presents with cyclical episodes of fever, chills, and sweating, typically every 48 to 72 hours, depending on the species. Other common symptoms include headache, muscle aches, fatigue, nausea, and vomiting [3, 4].

Human Immunodeficiency Virus (HIV) infection, which leads to Acquired Immunodeficiency Syndrome (AIDS), has a wide range of clinical manifestations. Acute HIV infection may present with a flu-like illness, including fever, rash, sore throat, swollen lymph nodes, and muscle and joint pain. As the infection progresses, chronic HIV may remain asymptomatic for years but eventually leads to immunosuppression, predisposing individuals to opportunistic infections and cancers. Symptoms in the advanced stages of AIDS can include severe weight loss, chronic diarrhea, prolonged fever, and opportunistic infections like Pneumocystis pneumonia, tuberculosis, and various fungal infections [5, 6].

Lyme disease, caused by the bacterium Borrelia burgdorferi and transmitted through tick bites, has three stages of clinical manifestations. Early localized Lyme disease presents with erythema migrans, a characteristic expanding rash often with a central clearing, along with flu-like symptoms such as fever, chills, fatigue, and muscle and joint aches. Early disseminated Lyme disease can lead to multiple rashes, neurological symptoms like facial palsy and meningitis, and cardiac manifestations such as heart block. Late Lyme disease may result in arthritis, particularly of large joints like the knee, and chronic neurological symptoms [7, 8].

COVID-19, caused by the SARS-CoV-2 virus, has a broad spectrum of clinical manifestations ranging from asymptomatic infection to severe respiratory illness and multi-organ failure. Common symptoms include fever, cough, shortness of breath, fatigue, muscle and body aches, headache, loss of taste or smell, sore throat, congestion or runny nose, nausea, vomiting, and diarrhea. Severe cases can lead to pneumonia, Acute Respiratory Distress Syndrome (ARDS), septic shock, and death. Long-term symptoms, known as "long COVID," can persist for months after the acute infection has resolved, affecting multiple organ systems and significantly impacting quality of life [9, 10].

Conclusion

The common cold, primarily caused by rhinoviruses, presents with a runny or stuffy nose, sneezing, sore throat, cough, mild headache, and body aches. Symptoms are generally mild and self-limiting, but can lead to complications like sinusitis, otitis media, or exacerbation of asthma in susceptible individuals.

References

  1. Rocha AF, Araújo MA, Barros VL, et al. Complications, clinical manifestations of congenital syphilis, and aspects related to its prevention: an integrative review.

    2. Rev Bras Enferm. 2021;74:e20190318.

    Indexed at, Google Scholar, Cross Ref

  2. Coffey S, Roberts-Thomson R, Brown A, et al. Global epidemiology of valvular heart disease. Nat Rev Cardiol. 2021;18(12):853-64.

    3. Indexed at, Google Scholar, Cross Ref

  3. Furtado JM, Simões M, Vasconcelos-Santos D, et al. Ocular syphilis. Surv Ophthalmol. 2022;67(2):440-62.

    4. Indexed at, Google Scholar, Cross Ref

  4. Cordero JH, Shepard Z, Schultz J, et al. Dermatologic Manifestations of Tick-borne Diseases in Travelers. Curr Trop Med Rep. 2021;8:99-103.

    5. Indexed at, Google Scholar, Cross Ref

  5. Chen Q, Li Z, Zeng X. Diagnostic strategies for oral manifestations of infectious diseases. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2021;50(2):141-7.

    6. Indexed at, Google Scholar, Cross Ref

  6. Shieh WJ. Human adenovirus infections in pediatric population-an update on clinico–pathologic correlation. Biomed J. 2022;45(1):38-49.

    7. Indexed at, Google Scholar, Cross Ref

  7. Schwartz DM, Kitakule MM, Dizon BL, et al. Systematic evaluation of nine monogenic autoinflammatory diseases reveals common and disease-specific correlations with allergy-associated features. Ann Rheum Dis. 2021;80(6):788-95.

    8. Indexed at, Google Scholar, Cross Ref

  8. D?ra M, Sticová E, Felšöová A, et al. Clinical and histopathological aspects of the most common inflammatory non-infectious skin diseases. Cesk Patol. 2023;59(3):104-23.

    9. Indexed at, Google Scholar

  9. Quinlan JD. Human papillomavirus: screening, testing, and prevention. Am Fam Physician. 2021;104(2):152-9.

    10. Indexed at, Google Scholar

  10. Zhang M, Wang H, Tang J, et al. Clinical characteristics of severe neonatal enterovirus infection: a systematic review. BMC Pediatr. 2021;21:1-2.

    11. Indexed at, Google Scholar, Cross Ref

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