Journal of Neurology and Neurorehabilitation Research

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Short Communication - Journal of Neurology and Neurorehabilitation Research (2024) Volume 9, Issue 6

Advances in Paediatric Neurology: Emerging Therapies and Innovations

Philip Groopman *

Division of Neurology, University Hospital Antwerp, Belgium

*Corresponding Author:
Philip Groopman
Division of Neurology, University Hospital Antwerp, Belgium
E-mail: groopman@uha.bl.org

Received: 22-Oct-2024, Manuscript No. JNNR-24-155317; Editor assigned: 23-Oct-2024, PreQC No. JNNR-24-155317(PQ); Reviewed: 06-Nov-2024, QC No. JNNR-24-155317; Revised: 12-Nov-2024, Manuscript No. JNNR-24-155317(R); Published: 19-Nov-2024, DOI: 10.35841/aajnnr-9.6.234

Citation: : Groopman P. Advances in paediatric neurology: Emerging therapies and innovations. J Neurol Neurorehab Res.2024;9(6):234

Introduction

Advances in pediatric neurology have significantly enhanced our ability to diagnose, treat, and manage neurological disorders in children [1]. As research continues to evolve, new therapies and innovations are transforming the landscape of pediatric care, offering hope for better outcomes in conditions that were once considered untreatable [2].

One of the most promising areas of progress in pediatric neurology is the development of targeted therapies [3]. In conditions like epilepsy, new antiepileptic drugs (AEDs) and advanced surgical interventions are improving seizure control in children [4]. For example, the use of responsive neurostimulation (RNS) systems has enabled real-time intervention for seizures, minimizing the need for invasive surgery and reducing seizure frequency in some patients [5]. Additionally, genetic therapies are showing potential in treating inherited neurological conditions such as spinal muscular atrophy (SMA) [6]. The approval of gene therapies like nusinersen (Spinraza) has provided a groundbreaking treatment for SMA, altering the course of the disease by targeting the genetic mutation responsible for the condition [7].

Another critical innovation is the growing application of neurogenetic testing. This technology allows for earlier and more accurate diagnoses of a wide range of neurological disorders, such as neurogenetic syndromes and neurodegenerative diseases [8]. Early diagnosis enables timely interventions, improving the long-term prognosis for many children [9]. For instance, advancements in genetic screening can help identify conditions like Rett syndrome and fragile X syndrome, leading to personalized treatment plans that better address the specific needs of each patient [10].

Conclusion

Moreover, neuroplasticity—the brain’s ability to reorganize itself in response to injury or disease—has become a focal point in pediatric neurology. Research into promoting neuroplasticity through rehabilitation therapies, stem cell treatments, and other regenerative approaches is opening new frontiers in pediatric neurology. These innovations are paving the way for treatments that can not only manage symptoms but potentially repair and restore function, offering new hope to children with neurological conditions.

References

  1. Buccilli B. Exploring new horizons: Emerging therapeutic strategies for pediatric stroke. Exp Neurol. 2024:114701.
  2. Indexed at, Google Scholar, Cross Ref

  3. Thomas AA, Brennan CW, DeAngelis LM, et al. Emerging therapies for glioblastoma. JAMA Neurol. 2014;71(11):1437-44.
  4. Indexed at, Google Scholar, Cross Ref

  5. Lambrecht S, Urra O, Grosu S, et al. Emerging rehabilitation in cerebral palsy. ETNR. 2014:23-49.
  6. Google Scholar

  7. Jacob SA, Talati R, Kanter J. The evolving treatment landscape for children with sickle cell disease. Lancet Child Adolesc Health. 2023;7(11):797-808.
  8. Indexed at, Google Scholar, Cross Ref

  9. Banerjee S, Booth CM, Bruera E, et al. Two decades of advances in clinical oncology—lessons learned and future directions. Nat Rev Clin Oncol. 2024:1-0.
  10. Indexed at, Google Scholar, Cross Ref

  11. Sakashita K, Komori K, Morokawa H, et al. Screening and interventional strategies for the late effects and toxicities of hematological malignancy treatments in pediatric survivors. Expert Rev Hematol. 2024.
  12. Indexed at, Google Scholar, Cross Ref

  13. Tan K, Yeo T, Yong KP, et al. Central nervous system inflammatory demyelinating diseases and neuroimmunology in Singapore—Epidemiology and evolution of an emerging subspecialty. Neurol. Clin. Neurosci. 2021;9(4):259-65.
  14. Google Scholar

  15. Damian A, Gozal D. Innovations in the Treatment of Pediatric Obstructive Sleep Apnea. Adv Exp Med Biol. 2022;11:339-350).
  16. Indexed at, Google Scholar, Cross Ref

  17. Hansen B. America's first medical breakthrough: how popular excitement about a French rabies cure in 1885 raised new expectations for medical progress. Am Hist Rev. 1998;103(2):373-418.
  18. Indexed at, Google Scholar

  19. Maher KO, Chang AC, Shin A, et al. Innovation in pediatric cardiac intensive care: an exponential convergence toward transformation of care. World J Pediatr Congenit Heart Surg. 2015;6(4):588-96.
  20. Indexed at, Google Scholar, Cross Ref

 

Get the App