Short Communication - Research and Reports in Gynecology and Obstetrics (2021) Volume 2, Issue 1

A unique polyherbal formulation BASANT cures vaginosis restoring healthy vagina, protects women from sexually transmitted infections and amazingly eliminates human papilloma virus from infected cervix.

Talwar G.P*, Jagdish C. Gupta, Rajyashri Sharma, B.C. Das, Kavita Bansal, Gustavo F. Doncel, John T. Schiller, Manoj K. Pastey, Aruna Mittal, Ajay George Varghese

Department of Medicine, 3Amity University, Uttar Pradesh, India.

 *Correspondence to Dr. Talwar GP, Department of Medicine Amity University Uttar Pradesh, India,E-mail: gptalwar@gmail.com.

Abstract

BASANT is composed of Curcumin (diferuloyl methane), Aloe vera, purified extracts of Amla (Emblica Officinalis) and Neem (Azadirachta Indica) along with pharmacopially approved excipients. It has remarkable efficacy of curing Vaginosis (abnormal vaginal discharge), restoring vaginal pH to 4.5 of healthy vagina. It is effective also in women incurable by antibiotics: Metronidazole, Clinmamycin plus chlortrimazole.

Description

BASANT is composed of Curcumin (diferuloyl methane), Aloe vera, purified extracts of Amla (Emblica Officinalis) and Neem (Azadirachta Indica) along with pharmacopially approved excipients. It has remarkable efficacy of curing Vaginosis (abnormal vaginal discharge), restoring vaginal pH to 4.5 of healthy vagina. It is effective also in women incurable by antibiotics: Metronidazole, Clinmamycin plus chlortrimazole [1]. BASANT inhibits the growth of all WHO strains and clinical isolates of N.gonorrhoeae, including those resistant to penicillin, tetracycline, nalidixic acid and ciproflaxin. It has pronounced inhibitory action against Candida glabrata, Candida albicans and Candida tropicalis isolated from women with vulvo-vaginal candidiasis, including those resistant to azole drugs and amphotericin B [2]. BASANT exercises high virucidal action against HIV and inhibits the entry of HIV in cells with either CCR5 or CXCR4 receptors. It not only kills HPV-16, but is also astonishingly effective in eliminating HPV-16 from infected cervical cells rendering the Pap smear to normal state. With due approval of Drugs Regulatory Authorities, it has undergone successfully safety and efficacy trials. It has been passed onto a company M/s Bipha Drug Laboratories, Kerala for making it available to public [3]. Vaginosis is a widely prevalent syndrome. A high percentage of women suffer from abnormal discharge and their vaginal pH goes above the normal healthy pH of 4.5. Insertion of one capsule of BASANT manually in the vagina for seven nights cures fully Vaginosis (Figure1). Summarizes the findings in a typical case [4]. Figure 1(a): Relief from abnormal vaginal discharge [5]. Figure 1(b): Disappearance of Clue cells. An illustrative representation of a typical woman suffering from recurring episodes of Vaginosis [6]. Short Commentary https://www.alliedacademies.org/research-and-reports-in-gynecology-andobstetrics/ 1 Res Report Gyn obs 2021 Volume 2 Issue 1 ON ENROLLMENT AFTER TREATMENT ON ENROLLMENT AFTER TREATMENT The abnormal vaginal discharge disappears revealing a healthy vagina. Also the abnormal Clue cells are no longer visible. The pH of vagina returns to 4.5, the pH of a healthy vagina. In many women, the unpleasant odour of an unhealthy vagina gets also cured [7]. Sexual tract infections BASANT inhibits all WHO strains and clinical isolates of Neisseria gonorrhoeae, including those resistant to penicillin, tetracycline, nalidixic acid and ciprofloxacin. It has also pronounced inhibitory action against Candida glabrata, Candida albicans and Candida tropicalis isolated from women with vulvovaginal candidiasis, including three isolates resistant to azole drugs and amphotericin [8]. BASANT inhibits Chlamydia trachomatis invitro and invivo (Figure 2). Figure 2: Inhibitory effects of BASANT on Chlamydia trachomatis serovar D (D/UW-3/Cx) using the post-infection incubation method. Standard deviations from triplicate tests are indicated by error bars. The minimum inhibitory concentration (MIC) was 8 µg/mL BASANT. IFU, inclusion forming units [9]. Efficacy against HIV: Then the great interest is its efficacy against HIV. It prevents the entry of HIV in lymphocytes of all strains tested including those employing either CCR4 or CCR5 receptors. Remarkable action of BASANT against Human Papilloma Virus (HPV) Carcinoma of cervix is a major cancer of women. It is initiated by infection of cervical cells by a virulent strain of HPV16 or HPV18. Initial infection of cells by HPV renders Pap smear abnormal [10]. In collaboration with Gynaecologists, we observed that treatment of women at early stage of infection, who are HPV16 positive, and whose Pap smear is abnormal, rendered every one of eleven out of eleven women tested, HPV16 negative from HPV16 positivity status.

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