Mini Review - Journal of Dermatology Research and Skin Care (2023) Volume 7, Issue 6
A brief note on causes, types, and treatment strategies of alopecia.
Bo Wang*
Department of Dermatology, Peking University People’s Hospital, Beijing, China
- *Corresponding Author:
- Bo Wang
Department of Dermatology
Peking University People’s Hospital, Beijing
China
E-mail: wang_b76@cpcm.ac.cn
Received:25-Nov-2023,Manuscript No. AADRSC-23-122503; Editor assigned: 27-Nov-2023, PreQC No. AADRSC-23-122503 (PQ); Reviewed:11-Dec-2023, QC No. AADRSC-23-122503; Revised:16-Dec-2023, Manuscript No. AADRSC-23-122503 (R); Published:23 -Dec-2023, DOI: 10.35841/aadrsc- 7.5.185
Citation: Wang B. A brief note on causes, types, and treatment strategies of alopecia. Dermatol Res Skin Care. 2023; 7(6):185
Introduction
Alopecia, a term encompassing various types of hair loss, is a condition that affects individuals of all ages and backgrounds. The impact of alopecia extends beyond mere physical changes, often influencing one's self-esteem and mental well-being. In this comprehensive article, we will delve into the intricacies of alopecia, exploring its causes, different types, and the diverse treatment strategies available for managing this condition. Alopecia refers to the partial or complete loss of hair from areas where it normally grows. It can manifest in different forms and affect various areas of the body, leading to distinct patterns of hair loss. According to the American Academy of Dermatology, alopecia is a common condition that affects millions of people worldwide, irrespective of age, gender, or ethnicity [1].
Causes of alopecia
Genetic factors: One of the primary causes of alopecia is genetics. Hereditary factors play a significant role in conditions like androgenetic alopecia, commonly known as male-pattern baldness or female-pattern baldness. Autoimmune disorders: Alopecia areata is an autoimmune condition where the immune system mistakenly attacks hair follicles, leading to hair loss. This type of alopecia can occur suddenly and result in small, round patches of baldness [2].
Hormonal changes: Fluctuations in hormone levels, such as those that occur during pregnancy, childbirth, or menopause, can contribute to alopecia. Conditions like polycystic ovary syndrome (PCOS) can also influence hair loss. Medical treatments: Certain medical treatments, such as chemotherapy used in cancer treatment, can result in significant hair loss. However, hair often regrows once the treatment is completed. Infections and diseases: Scalp infections, such as ringworm, and certain diseases like lupus and diabetes, can contribute to alopecia [3].
Types of alopecia
Androgenetic alopecia: Androgenetic alopecia is the most common form of hair loss and is often hereditary. It is characterized by a gradual thinning of hair, typically in a specific pattern, such as a receding hairline in men or widening part in women [4].
Alopecia Areata: Alopecia areata is an autoimmune disorder that results in unpredictable, patchy hair loss. It can affect the scalp or other areas of the body where hair is present, such as the eyebrows or beard. Alopecia totalis and alopecia universalis: In more severe cases, alopecia areata can progress to alopecia totalis, involving the complete loss of scalp hair, or alopecia universalis, which leads to the loss of all body hair [5].
Traction alopecia: Traction alopecia is caused by constant pulling or tension on the hair, often due to hairstyles that pull the hair tightly. This condition is common in individuals who frequently wear tight braids, ponytails, or hair extensions [6].
Telogen effluvium: Telogen effluvium is a temporary form of hair loss that occurs when a significant number of hair follicles enter the resting phase of the hair growth cycle simultaneously. This can be triggered by factors such as severe stress, illness, or certain medications [7].
Diagnosing alopecia
Medical evaluation: When experiencing significant hair loss, it is crucial to seek medical advice. A dermatologist or healthcare professional specializing in hair disorders will conduct a thorough examination of the scalp, hair, and medical history to determine the underlying cause of alopecia. Scalp biopsy: In some cases, a scalp biopsy may be recommended to examine a small tissue sample under a microscope. This can help identify the type of alopecia and guide treatment decisions [8].
Blood tests: Blood tests may be conducted to check for underlying medical conditions, hormonal imbalances, or nutritional deficiencies that could contribute to hair loss. Living with alopecia Psychological impact: The emotional and psychological impact of alopecia should not be underestimated. Hair loss can affect self-esteem, body image, and overall quality of life. Support groups, counselling, and education about the condition are essential aspects of holistic care for individuals with alopecia [9].
Wigs and hairpieces: Many individuals with alopecia choose to wear wigs or hairpieces as a cosmetic solution. High quality, natural-looking options are available, providing a sense of normalcy and confidence. Support groups and advocacy: Engaging with support groups and advocacy organizations dedicated to alopecia can provide valuable resources, shared experiences, and a sense of community. These platforms foster understanding and acceptance, empowering individuals to navigate the challenges of living with hair loss [10].
Conclusion
Alopecia is a multifaceted condition with diverse causes and manifestations, impacting individuals physically, emotionally, and socially. Understanding the underlying factors, seeking timely medical advice, and exploring appropriate treatment options are crucial steps in managing alopecia effectively. With on-going research and a comprehensive approach to care, individuals with alopecia can lead fulfilling lives and embrace their unique journey.
References
- Toussi A, Barton VR, Le ST, et al. Psychosocial and psychiatric comorbidities and health-related quality of life in alopecia areata: A systematic review. J Am Acad Dermatol. 2021;85(1):162-75.
- Rajabi F, Drake LA, Senna MM, et al. Alopecia areata: A review of disease pathogenesis. Br J Dermatol. 2018;179(5):1033-48.
- Phan K, Sebaratnam DF. JAK inhibitors for alopecia areata: A systematic review and meta? J Eur Acad Dermatol Venereol. 2019;33(5):850-6.
- Petukhova L, Christiano AM. Functional interpretation of genome-wide association study evidence in alopecia areata. J Invest Dermatol. 2016;136(1):314.
- Wang EH, Yu M, Breitkopf T, et al. Identification of autoantigen epitopes in alopecia areata. J Invest Dermatol. 2016;136(8):1617-26.
- Gilhar A, Assy B, Shalaginov R, et al. Melanocyte-associated T cell epitopes can function as autoantigens for transfer of alopecia areata to human scalp explants on Prkdcscid mice. J Invest Dermatol. 2001;117(6):1357-62.
- Yenin JZ, Serarslan G, Yönden Z, et al. Investigation of oxidative stress in patients with alopecia areata and its relationship with disease severity, duration, recurrence and pattern. Clin Exp Dermatol. 2015;40(6):617-21.
- Acharya P, Mathur MC. Oxidative stress in alopecia areata: A systematic review and meta? Int J Dermatol. 2020;59(4):434-40.
- Zhao Y, Zhang B, Caulloo S, et al. Diffuse alopecia areata is associated with intense inflammatory infiltration and CD8+ T cells in hair loss regions and an increase in serum IgE level. Indian J Dermatol Venereol Leprol. 2012;78:709.
- Li SF, Zhang XT, Qi SL, et al. Allergy to dust mites may contribute to early onset and severity of alopecia areata. Clin Exp Dermatol. 2015;40(2):171-6.
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