Research Article - Biomedical Research (2016) Volume 27, Issue 4

Synthesis of 4-arylpolyhydroquinoline derivatives and evaluation of their anti-inflammatory on endometritis

Four novel 4-arylpolyhydroquinoline derivatives (1-4) were synthesized and characterized via IR, 1H NMR, HRMS, and single crystal X-ray crystallography. The experimental results of anti-inflammatory activity showed that compared with compounds 1 and 2, compounds 3 and 4 with electron-repelling groups in the phenyl ring exerted rather potent activities.

Author(s): Ling-Ling Teng, Xin-Ling Zhou, Guang-Zhen Ma

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