Mini Review - Journal of Gastroenterology and Digestive Diseases (2022) Volume 7, Issue 6
Role of the brain-gut axis dysfunction in potential mechanism digestion.
Early childhood stress has been linked to a variety of psychiatric diseases, including depression and anxiety. Separation from one's mother is a well-studied model of early life trauma in rodents. Stress, on the other hand, causes changes in many systems throughout the body during this important period. As a result, a variety of different conditions linked to adversity in childhood frequently coexist with psychiatric illnesses, implying a shared aetiology. Irritable Bowel Syndrome (IBS) is a functional gastrointestinal condition hypothesised to be caused by a faulty brain-gut relationship. Spinal pathways, the hypothalamus pituitary adrenal axis, the immune system, and the enteric micro biota are all important parts of the brain–gut axis. Stress, especially early in life, appears to be a predisposing factor, according to growing data.
Author(s): Damon Jhon