+441518081136Mini Review - Journal of Medical Oncology and Therapeutics (2022) Volume 7, Issue 4
Molecular mechanisms of interaction between autophagy and digestion system in cancer.
Intriguingly, numerous highlights of the metastatic tumour cell, whether that be mesenchymal properties or capacity to elude safe reconnaissance, are related with a stem-like phenotype and linked to medicate resistance. Autophagy is upregulated in essential human breast, glioblastoma, melanoma, oesophageal cancer, and hepatocellular carcinoma upon movement to progressed metastatic disease and expression of autophagy markers in these cancers is related with destitute forecast, highlighting novel and imperative parts for autophagy at diverse focuses within the metastatic cascade.
Author(s): Akemi Tanaka*