Research Article - Asian Journal of Biomedical and Pharmaceutical Sciences (2017) Volume 7, Issue 60

Laparoscopic Sleeve Gastrectomy, as an Ultimate Intervention for Fatness Treatment, Make Improved Physiological Changes in Obese Patients

Background: Obesity and related comorbidities such as diabetes, coronary heart diseases and nonalcoholic fatty liver are both health and socioeconomically problem worldwide. Determining an appropriate treatment of morbid obesity is a multidisciplinary approach. In recent years, Laparoscopic Sleeve Gastrectomy (LSG) has become the first choice of surgical treatment for the morbid obesity patients resistant to the traditional diet methods, exercise and medications. Material and methods: We retrospectively analyzed the results of first 100 consecutive cases underwent LSG between January 2015 and January 2016 in our center. Patient demographics (age, gender) were recorded and Patient’s body mass indexes (BMI), fasting blood sugar (FBS), Lipid parameter (LDL, HDL) levels, Liver Enzyme (AST, ALT) levels, Blood Pressures and other comorbidities were compared between one week before and after six months of surgery. Surgical complications were also recorded. Results: BMIs, Levels of FBS, blood pressure, liver enzymes and lipid profile components significantly reduced (P<0.05). Comorbid conditions like hypertension, obstructive sleep apnea, mostly resolved or improved. A case of leakage resulted in pelvic abscess; laparotomy and drainage was performed. Another leakage gave rise to the gastrobronchial fistula which couldn’t be corrected by endoscopic methods. Patient finally underwent thoracotomy and lung segmentectomy. One patient had micro anastomotic leak and was observed nonoperatively. No mortality occurred. Conclusion: Although it may cause some major complications, LSG is effective operation to treat morbid obese patients. Comorbid conditions fastly resolve even within the months, synchronous with the weight loss.

Author(s): Mustafa Erol, Nazim Gures

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