Research Article - Journal of RNA and Genomics (2021) Volume 17, Issue 0

Impact of glyphosate on IGF beta and TNF alpha exposure on male wistar rats.

Glyphosate is a herbicide that inhibits the plant enzyme. It is commercially available in the form of roundup. High exposure to roundup causes necrosis that damages the leydig cells and other cells of the rat. There is a decrease in the normal sperm count due to a decrease in the concentration of histone-1 and protamine-1. The insulin-like growth factor is produced by osteoblasts which are the bone-forming cells of the body. IGF is also important in maintaining the effect of systemic hormones on bone formation. TNF alpha is a tumor necrosis factor which is produced by macrophages that is responsible for the destruction of tumor cell lines.

Author(s): Medha Rajiv Ranjan, Kavitha S*, Selvaraj J, V Vishnupriya, Gayathri R

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