Commentary - Journal of Gastroenterology and Digestive Diseases (2022) Volume 7, Issue 6
Impact of Gastrointestinal (GI) nematode infections on humans in low income countries.
The primary ruminant gastrointestinal nematode parasites are all members of the Strongylida order and the Trichostrongyloidea family. Despite their close evolutionary link, there are major distinctions in the microenvironmental niches filled by the various parasite developmental phases, which may account for the diverse parasite species' vulnerability to the host's immune effector mechanisms. Furthermore, resistance has been seen in distinct forms against the adult and larval stages of the same parasite species, as well as against the same parasite stage. It has been shown that infective larval stages of gastrointestinal nematode parasites can be rejected both quickly and slowly. This review will provide an overview of the many manifestations of resistance to ruminant gastrointestinal nematode infections, as well as recommendations for further research.
Author(s): Ito Miura