Research Article - Biomedical Research (2019) Volume 30, Issue 5

Evaluation of 5-aminolevulinic acids induced photodynamic inactivation on Streptococcus mutans and Streptococcus sobrinus; by using two light emitting diode wavelengths (In vitro study).

The aim of this study was to evaluate the effect of photoactive-dye (5- aminolevulinic acid) in inhibition of Streptococcus mutans and Streptococcus sobrinus by using different light emitting diode wavelengths (Red light 635 nm and Blue light 440 nm). The minimum inhibitory concentration and minimum bactericidal concentration was determined by using 96-well plate in a dark room. The result of the study exhibited that both types of bacteria were inactivated but at different concentration, the S. mutans was inhibeted at 64.5 mM whereas, the S. sobrinus show inhibition at 32.25 mM, both types of light were capable to activating the 5- aminolevulinic acid and lead to significant reduction in Mutans Streptococci and Sobrinus Streptococci. But the Mutans Streptococci need more concentration to be in activated this may be due to the type of bacterial gene.

Author(s): Hawzhen Masoud M Saeed, Bestoon Mohammad Faraj, Balssam Mohammad Mirdan

Abstract Full Text PDF