Research Article - Biomedical Research (2017) Volume 28, Issue 14

Evaluation and analysis of phytochemical antioxidant capacity

According to previous studies, phytochemicals have many pharmacological activities. Chinese herbal remedies that have potential use in many diseases. Caffeic acid, p-coumaric acid, oleanolic acid and ursolic acid are bioactive compounds from plants. In the present study, the antioxidant properties of the caffeic acid, p-coumaric acid, oleanolic acid and ursolic acid were evaluated by using different in vitro antioxidant assays such as 1, 1-diphenyl-2-picryl-hydrazyl free radical (DPPH•) scavenging, metal chelating activities and cytochrome c reduced method. The result of this study showed that caffeic acid, p-coumaric acid, oleanolic acid and ursolic acid all have apparent antioxidant activity by these assays. Among these compounds, oleanolic acid was capable of inhibiting xanthine oxidase and showed a significant antioxidant effect. Thus, these compounds have potential to be used as natural antioxidants against oxidative deprivation for preventing carcinogenesis and other diseases.

Author(s): Mei-Yin Chang, Chi-Ming Liu, Den-En Shieh, Chung-Yi Chen

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