Research Article - Journal of Clinical Ophthalmology (2024) Volume 8, Issue 3

Efficacy of accelerated corneal cross-linking for the treatment of progressive keratoconus: Two-year's outcomes.

Purpose: To evaluate the long-term results of accelerated Corneal Cross-Linking (CXL) in Yemeni patients with progressive keratoconus, between January 2016 and January 2018.

Methods: Fifty eyes of 32 patients were record complete follow up for 2 years, underwent accelerated CXL at 18 mW/cm² for 5 minutes in one eye. The follow-up visits were scheduled on second day, 5^th day, 12^th, 18^th, and 24 months after the treatment.

Results: There were highly significant improvement in Kmax, and Kmean preoperative and two years postoperative, (P=0.006) and (P=0.000). We noted a significant flattening of keratometry, Kmax flattened by 0.5 diopter, and Kmean, by 0.33 diopter, of the cornea. Pachymetry apex decreased during two years follow up with (p=0.001), (p=0.009), but was stable after CXL follow up (p=0.38). In terms of thinnest corneal thickness there was decrease in the corneal thickens after CXL two years later (P=0.006), while after the treatment it was stable during the study period with (P=0.156). The best spectacle-corrected visual acuity showed improvement over the entire two year’s follow-up with (p=0.027).

Conclusion: Accelerated CXL is an effective treatment method to prevent progression in young patients with progressive keratoconus without the occurrence of serious complications or side effects.

Author(s): Abdulmoghni O. Al-Barrag*, Ahmed M. Al-Asbahi

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