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Research Article - Journal of Clinical Pathology and Laboratory Medicine (2024) Volume 6, Issue 1
Current knowledge regarding the biochemical methods for assessing oxidative stress in human serum
This editorial summarizes the information available currently regarding the different biochemical techniques for assessing the level of oxidative stress in human serum. The methods include the determination of the concentration of Reactive Oxygen Species (ROS) (direct measurement), the antioxidant enzyme activity, and the concentration of antioxidant molecules (non-enzymatic antioxidants), the concentration of oxidative damage biomarkers, the Total Antioxidant Capacity (TAC), and Oxidative Stress Index (OSI). Each approach has advantages and disadvantages, and the optimal strategy may change based on the specific research question or biomedical application. Therefore, it is essential to carefully consider the benefits and weaknesses of each method before selecting the optimal one for identifying oxidative stress in human serum. Moreover, combining various methods can provide a more accurate assessment of the oxidative stress level in the human organism.
Author(s): Delimaris I