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Mini Review - Journal of Cholesterol and Heart Disease (2023) Volume 7, Issue 3
Cardiac Remodeling in Cardiomyopathy: Insights into Cellular and Extracellular Matrix Interactions
Cardiomyopathy is a complex and heterogeneous group of diseases characterized by structural and functional abnormalities of the heart muscle. One of the key processes involved in the progression of cardiomyopathy is cardiac remodeling, which refers to the alterations in the structure and function of the heart in response to various pathological stimuli. In this article, we delve into the cellular and extracellular matrix interactions that underlie cardiac remodeling in cardiomyopathy. We discuss the molecular mechanisms and signaling pathways involved, highlighting the role of cellular components and the extracellular matrix in mediating these processes. Understanding these interactions can provide valuable insights into the pathogenesis of cardiomyopathy and may open new avenues for therapeutic interventions to prevent or reverse adverse cardiac remodeling.
Author(s): Chen Huang